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Detection of Microsatellite Instability: State of the Art and Future Applications in Circulating Tumour DNA (ctDNA)

SIMPLE SUMMARY: Microsatellite instability (MSI) is a molecular fingerprint for defects in the mismatch repair system (dMMR) and is associated with higher risks of cancers. MSI/dMMR tumours are characterized by the accumulation of mutations throughout the genome, and particularly in microsatellite (...

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Detalles Bibliográficos
Autores principales:	Gilson, Pauline, Merlin, Jean-Louis, Harlé, Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037825/ https://www.ncbi.nlm.nih.gov/pubmed/33804907 http://dx.doi.org/10.3390/cancers13071491

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