BRAF Gene and Melanoma: Back to the Future

As widely acknowledged, 40–50% of all melanoma patients harbour an activating BRAF mutation (mostly BRAF V600E). The identification of the RAS–RAF–MEK–ERK (MAP kinase) signalling pathway and its targeting has represented a valuable milestone for the advanced and, more recently, for the completely re...

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Detalles Bibliográficos
Autores principales: Ottaviano, Margaret, Giunta, Emilio Francesco, Tortora, Marianna, Curvietto, Marcello, Attademo, Laura, Bosso, Davide, Cardalesi, Cinzia, Rosanova, Mario, De Placido, Pietro, Pietroluongo, Erica, Riccio, Vittorio, Mucci, Brigitta, Parola, Sara, Vitale, Maria Grazia, Palmieri, Giovannella, Daniele, Bruno, Simeone, Ester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037827/
https://www.ncbi.nlm.nih.gov/pubmed/33801689
http://dx.doi.org/10.3390/ijms22073474

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