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On the Origins of Homology Directed Repair in Mammalian Cells

Over the course of the last five years, expectations surrounding our capacity to selectively modify the human genome have never been higher. The reduction to practice site-specific nucleases designed to cleave at a unique site within the DNA is now centerstage in the development of effective molecul...

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Detalles Bibliográficos
Autores principales: Sansbury, Brett M., Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8037881/
https://www.ncbi.nlm.nih.gov/pubmed/33805897
http://dx.doi.org/10.3390/ijms22073348