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QSAR and Pharmacophore Modeling of Nitrogen Heterocycles as Potent Human N-Myristoyltransferase (Hs-NMT) Inhibitors

N-myristoyltransferase (NMT) is an important eukaryotic monomeric enzyme which has emerged as an attractive target for developing a drug for cancer, leishmaniasis, ischemia-reperfusion injury, malaria, inflammation, etc. In the present work, statistically robust machine leaning models (QSAR (Quantit...

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Detalles Bibliográficos
Autores principales:	Zaki, Magdi E. A., Al-Hussain, Sami A., Masand, Vijay H., Akasapu, Siddhartha, Lewaa, Israa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038050/ https://www.ncbi.nlm.nih.gov/pubmed/33805223 http://dx.doi.org/10.3390/molecules26071834

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