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Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells

The carbazole compounds PK9320 (1-(9-ethyl-7-(furan-2-yl)-9H-carbazol-3-yl)-N-methylmethanamine) and PK9323 (1-(9-ethyl-7-(thiazol-4-yl)-9H-carbazol-3-yl)-N-methylmethanamine), second-generation analogues of PK083 (1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine), restore p53 signaling in Y220C p53...

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Detalles Bibliográficos
Autores principales: Luparello, Claudio, Cruciata, Ilenia, Joerger, Andreas C., Ocasio, Cory A., Jones, Rhiannon, Tareque, Raysa Khan, Bagley, Mark C., Spencer, John, Walker, Martin, Austin, Carol, Ferrara, Tiziana, D′Oca, Pietro, Bellina, Rossella, Branni, Rossella, Caradonna, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038095/
https://www.ncbi.nlm.nih.gov/pubmed/33810274
http://dx.doi.org/10.3390/ijms22073410