Cargando…
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells
The carbazole compounds PK9320 (1-(9-ethyl-7-(furan-2-yl)-9H-carbazol-3-yl)-N-methylmethanamine) and PK9323 (1-(9-ethyl-7-(thiazol-4-yl)-9H-carbazol-3-yl)-N-methylmethanamine), second-generation analogues of PK083 (1-(9-ethyl-9H-carbazol-3-yl)-N-methylmethanamine), restore p53 signaling in Y220C p53...
Autores principales: | Luparello, Claudio, Cruciata, Ilenia, Joerger, Andreas C., Ocasio, Cory A., Jones, Rhiannon, Tareque, Raysa Khan, Bagley, Mark C., Spencer, John, Walker, Martin, Austin, Carol, Ferrara, Tiziana, D′Oca, Pietro, Bellina, Rossella, Branni, Rossella, Caradonna, Fabio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038095/ https://www.ncbi.nlm.nih.gov/pubmed/33810274 http://dx.doi.org/10.3390/ijms22073410 |
Ejemplares similares
-
Trans- and Multigenerational Effects of Isothiazolinone Biocide CMIT/MIT on Genotoxicity and Epigenotoxicity in Daphnia magna
por: Kim, Jiwan, et al.
Publicado: (2023) -
Genotoxic and epigenotoxic effects in mice exposed to concentrated ambient fine particulate matter (PM(2.5)) from São Paulo city, Brazil
por: de Oliveira, Antonio Anax Falcão, et al.
Publicado: (2018) -
Establishment and Preliminary Characterization of Three Astrocytic Cells Lines Obtained from Primary Rat Astrocytes by Sub-Cloning
por: Caradonna, Fabio, et al.
Publicado: (2020) -
Cytotoxic Activity of the Histone Deacetylase 3-Selective Inhibitor Pojamide on MDA-MB-231 Triple-Negative Breast Cancer Cells
por: Luparello, Claudio, et al.
Publicado: (2019) -
Targeting Cavity-Creating p53 Cancer Mutations with
Small-Molecule Stabilizers: the Y220X Paradigm
por: Bauer, Matthias R., et al.
Publicado: (2020)