Cargando…

Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis

The aim of the present work was the application of hair biomonitoring to investigate exposure to pesticides in children and their parents residing in a vineyard area. Thirty-three children and 16 parents were involved in the study. Hair samples were self-collected before and after the application se...

Descripción completa

Detalles Bibliográficos
Autores principales: Polledri, Elisa, Mercadante, Rosa, Consonni, Dario, Fustinoni, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038297/
https://www.ncbi.nlm.nih.gov/pubmed/33918339
http://dx.doi.org/10.3390/ijerph18073723
_version_ 1783677342765285376
author Polledri, Elisa
Mercadante, Rosa
Consonni, Dario
Fustinoni, Silvia
author_facet Polledri, Elisa
Mercadante, Rosa
Consonni, Dario
Fustinoni, Silvia
author_sort Polledri, Elisa
collection PubMed
description The aim of the present work was the application of hair biomonitoring to investigate exposure to pesticides in children and their parents residing in a vineyard area. Thirty-three children and 16 parents were involved in the study. Hair samples were self-collected before and after the application season (PRE- and POST-EXP samples). Information on study subjects and the use of pesticides in the area were obtained. Thirty-nine pesticides were analyzed by liquid chromatography tandem mass spectrometry, and thirty-one pesticides were quantifiable in at least one hair sample. Most frequently detected pesticides were chlorpyrifos, cycloxidim, dimethomorph, metalaxyl, spiroxamine, and tetraconazole. From PRE-EXP to POST-EXP the percentage of quantification and/or the concentration of pesticides increased; the concentration was typically in the low pg/mg hair range with comparable levels in children and parents. An inverse correlation was found between the total exposure to pesticides in POST-EXP hair samples and the distance between home and the treated fields (Spearman ρ = −0.380, p = 0.01). The results of this study show that the majority of the study pesticides were measured in the hair of subjects living in the close proximity of treated vineyards, supporting the determination of pesticides in hair for the purpose of biomonitoring cumulative exposure in the general population.
format Online
Article
Text
id pubmed-8038297
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-80382972021-04-12 Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis Polledri, Elisa Mercadante, Rosa Consonni, Dario Fustinoni, Silvia Int J Environ Res Public Health Article The aim of the present work was the application of hair biomonitoring to investigate exposure to pesticides in children and their parents residing in a vineyard area. Thirty-three children and 16 parents were involved in the study. Hair samples were self-collected before and after the application season (PRE- and POST-EXP samples). Information on study subjects and the use of pesticides in the area were obtained. Thirty-nine pesticides were analyzed by liquid chromatography tandem mass spectrometry, and thirty-one pesticides were quantifiable in at least one hair sample. Most frequently detected pesticides were chlorpyrifos, cycloxidim, dimethomorph, metalaxyl, spiroxamine, and tetraconazole. From PRE-EXP to POST-EXP the percentage of quantification and/or the concentration of pesticides increased; the concentration was typically in the low pg/mg hair range with comparable levels in children and parents. An inverse correlation was found between the total exposure to pesticides in POST-EXP hair samples and the distance between home and the treated fields (Spearman ρ = −0.380, p = 0.01). The results of this study show that the majority of the study pesticides were measured in the hair of subjects living in the close proximity of treated vineyards, supporting the determination of pesticides in hair for the purpose of biomonitoring cumulative exposure in the general population. MDPI 2021-04-02 /pmc/articles/PMC8038297/ /pubmed/33918339 http://dx.doi.org/10.3390/ijerph18073723 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Polledri, Elisa
Mercadante, Rosa
Consonni, Dario
Fustinoni, Silvia
Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title_full Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title_fullStr Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title_full_unstemmed Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title_short Cumulative Pesticides Exposure of Children and Their Parents Living near Vineyards by Hair Analysis
title_sort cumulative pesticides exposure of children and their parents living near vineyards by hair analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038297/
https://www.ncbi.nlm.nih.gov/pubmed/33918339
http://dx.doi.org/10.3390/ijerph18073723
work_keys_str_mv AT polledrielisa cumulativepesticidesexposureofchildrenandtheirparentslivingnearvineyardsbyhairanalysis
AT mercadanterosa cumulativepesticidesexposureofchildrenandtheirparentslivingnearvineyardsbyhairanalysis
AT consonnidario cumulativepesticidesexposureofchildrenandtheirparentslivingnearvineyardsbyhairanalysis
AT fustinonisilvia cumulativepesticidesexposureofchildrenandtheirparentslivingnearvineyardsbyhairanalysis