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Combination of PKCδ Inhibition with Conventional TKI Treatment to Target CML Models
SIMPLE SUMMARY: The tyrosine kinase inhibitor (TKI) imatinib was the first targeted therapy to show clinical efficacy against chronic myeloid leukemia (CML) through inhibition of the breakpoint cluster region–Abelson murine leukemia viral oncogene homolog (BCR-ABL), which is responsible for the dise...
Autores principales: | Muselli, Fabien, Mourgues, Lucas, Morcos, Rita, Rochet, Nathalie, Nebout, Marielle, Guerci-Bresler, Agnès, Faller, Douglas V, William, Robert M, Mhaidly, Rana, Verhoeyen, Els, Legros, Laurence, Peyron, Jean-François, Mary, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038300/ https://www.ncbi.nlm.nih.gov/pubmed/33918475 http://dx.doi.org/10.3390/cancers13071693 |
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