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Synthesis and Biological Screening of New Cyano-Substituted Pyrrole Fused (Iso)Quinoline Derivatives

Several new cyano-substituted derivatives with pyrrolo[1,2-a]quinoline and pyrrolo[2,1-a]isoquinoline scaffolds were synthesized by the [3 + 2] cycloaddition of (iso)quinolinium ylides to fumaronitrile. The cycloimmonium ylides reacted in situ as 1,3-dipoles with fumaronitrile to selectively form di...

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Detalles Bibliográficos
Autores principales:	Al-Matarneh, Maria Cristina, Amărandi, Roxana-Maria, Mangalagiu, Ionel I., Danac, Ramona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038376/ https://www.ncbi.nlm.nih.gov/pubmed/33916806 http://dx.doi.org/10.3390/molecules26072066

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