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Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case

Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary p...

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Autores principales: Lalla, Francesca, Vinciguerra, Alessandro, Lissoni, Alessandra, Arrigoni, Gianluigi, Lira Luce, Francesca, Abati, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038516/
https://www.ncbi.nlm.nih.gov/pubmed/33916539
http://dx.doi.org/10.3390/ijerph18073762
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author Lalla, Francesca
Vinciguerra, Alessandro
Lissoni, Alessandra
Arrigoni, Gianluigi
Lira Luce, Francesca
Abati, Silvio
author_facet Lalla, Francesca
Vinciguerra, Alessandro
Lissoni, Alessandra
Arrigoni, Gianluigi
Lira Luce, Francesca
Abati, Silvio
author_sort Lalla, Francesca
collection PubMed
description Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP). We present a case of EMP arising as asymptomatic erythroplakia of the palate, which is rarely described in the literature. The definitive diagnosis was obtained with immunohistochemical studies, after which the lesion was subjected to excisional biopsy. At present, after two years of close follow-up, the patient has shown no signs of relapse or conversion to MM. The uniqueness of the case highlights the possibility of an atypical EMP lesion in the head and neck, thus posing a diagnostic and therapeutic challenge for physicians.
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spelling pubmed-80385162021-04-12 Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case Lalla, Francesca Vinciguerra, Alessandro Lissoni, Alessandra Arrigoni, Gianluigi Lira Luce, Francesca Abati, Silvio Int J Environ Res Public Health Case Report Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP). We present a case of EMP arising as asymptomatic erythroplakia of the palate, which is rarely described in the literature. The definitive diagnosis was obtained with immunohistochemical studies, after which the lesion was subjected to excisional biopsy. At present, after two years of close follow-up, the patient has shown no signs of relapse or conversion to MM. The uniqueness of the case highlights the possibility of an atypical EMP lesion in the head and neck, thus posing a diagnostic and therapeutic challenge for physicians. MDPI 2021-04-04 /pmc/articles/PMC8038516/ /pubmed/33916539 http://dx.doi.org/10.3390/ijerph18073762 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Lalla, Francesca
Vinciguerra, Alessandro
Lissoni, Alessandra
Arrigoni, Gianluigi
Lira Luce, Francesca
Abati, Silvio
Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title_full Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title_fullStr Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title_full_unstemmed Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title_short Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
title_sort solitary extramedullary plasmacytoma presenting as asymptomatic palatal erythroplakia: report of a case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038516/
https://www.ncbi.nlm.nih.gov/pubmed/33916539
http://dx.doi.org/10.3390/ijerph18073762
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