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Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case
Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary p...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038516/ https://www.ncbi.nlm.nih.gov/pubmed/33916539 http://dx.doi.org/10.3390/ijerph18073762 |
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author | Lalla, Francesca Vinciguerra, Alessandro Lissoni, Alessandra Arrigoni, Gianluigi Lira Luce, Francesca Abati, Silvio |
author_facet | Lalla, Francesca Vinciguerra, Alessandro Lissoni, Alessandra Arrigoni, Gianluigi Lira Luce, Francesca Abati, Silvio |
author_sort | Lalla, Francesca |
collection | PubMed |
description | Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP). We present a case of EMP arising as asymptomatic erythroplakia of the palate, which is rarely described in the literature. The definitive diagnosis was obtained with immunohistochemical studies, after which the lesion was subjected to excisional biopsy. At present, after two years of close follow-up, the patient has shown no signs of relapse or conversion to MM. The uniqueness of the case highlights the possibility of an atypical EMP lesion in the head and neck, thus posing a diagnostic and therapeutic challenge for physicians. |
format | Online Article Text |
id | pubmed-8038516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-80385162021-04-12 Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case Lalla, Francesca Vinciguerra, Alessandro Lissoni, Alessandra Arrigoni, Gianluigi Lira Luce, Francesca Abati, Silvio Int J Environ Res Public Health Case Report Solitary plasmacytoma (SP) is a rare malignant tumor of plasma cells with no systemic spread; however, when it disseminates and affects multiple skeletal sites, it is called multiple myeloma (MM). The etiology of solitary plasmacytoma is unknown, with two possible subtypes: solitary extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP). We present a case of EMP arising as asymptomatic erythroplakia of the palate, which is rarely described in the literature. The definitive diagnosis was obtained with immunohistochemical studies, after which the lesion was subjected to excisional biopsy. At present, after two years of close follow-up, the patient has shown no signs of relapse or conversion to MM. The uniqueness of the case highlights the possibility of an atypical EMP lesion in the head and neck, thus posing a diagnostic and therapeutic challenge for physicians. MDPI 2021-04-04 /pmc/articles/PMC8038516/ /pubmed/33916539 http://dx.doi.org/10.3390/ijerph18073762 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Lalla, Francesca Vinciguerra, Alessandro Lissoni, Alessandra Arrigoni, Gianluigi Lira Luce, Francesca Abati, Silvio Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title | Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title_full | Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title_fullStr | Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title_full_unstemmed | Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title_short | Solitary Extramedullary Plasmacytoma Presenting as Asymptomatic Palatal Erythroplakia: Report of a Case |
title_sort | solitary extramedullary plasmacytoma presenting as asymptomatic palatal erythroplakia: report of a case |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038516/ https://www.ncbi.nlm.nih.gov/pubmed/33916539 http://dx.doi.org/10.3390/ijerph18073762 |
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