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Succinate Anaplerosis Has an Onco-Driving Potential in Prostate Cancer Cells
SIMPLE SUMMARY: Depending on the availability of nutrients and increased metabolic demands, tumor cells rearrange their metabolism to survive and, ultimately, proliferate. Here, the authors investigated the effect of succinate, a metabolite of the mitochondrial citric acid cycle, on malignant and no...
Autores principales: | Sant’Anna-Silva, Ana Carolina B., Perez-Valencia, Juan A., Sciacovelli, Marco, Lalou, Claude, Sarlak, Saharnaz, Tronci, Laura, Nikitopoulou, Efterpi, Meszaros, Andras T., Frezza, Christian, Rossignol, Rodrigue, Gnaiger, Erich, Klocker, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038717/ https://www.ncbi.nlm.nih.gov/pubmed/33917317 http://dx.doi.org/10.3390/cancers13071727 |
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