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Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)

Background: This study aims to evaluate the clinical characteristics, complications, degree of glycemic control, and cardiovascular risk factor control in patients with type 1 diabetes in Catalonia (Northwest of Spain). Methods: Cross-sectional study using a database including clinical, laboratory,...

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Autores principales: Gimenez-Perez, Gabriel, Franch-Nadal, Josep, Ortega, Emilio, Mata-Cases, Manel, Goday, Albert, Real, Jordi, Rodriguez, Angel, Vlacho, Bogdan, Mauricio, Dídac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038775/
https://www.ncbi.nlm.nih.gov/pubmed/33917523
http://dx.doi.org/10.3390/jcm10071536
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author Gimenez-Perez, Gabriel
Franch-Nadal, Josep
Ortega, Emilio
Mata-Cases, Manel
Goday, Albert
Real, Jordi
Rodriguez, Angel
Vlacho, Bogdan
Mauricio, Dídac
author_facet Gimenez-Perez, Gabriel
Franch-Nadal, Josep
Ortega, Emilio
Mata-Cases, Manel
Goday, Albert
Real, Jordi
Rodriguez, Angel
Vlacho, Bogdan
Mauricio, Dídac
author_sort Gimenez-Perez, Gabriel
collection PubMed
description Background: This study aims to evaluate the clinical characteristics, complications, degree of glycemic control, and cardiovascular risk factor control in patients with type 1 diabetes in Catalonia (Northwest of Spain). Methods: Cross-sectional study using a database including clinical, laboratory, and treatment data. Patients with an ICD10 diagnosis of type 1 diabetes were included, excluding those treated with glucose-lowering agents other than insulin, or treated only with basal insulin two years after diagnosis. Results: 15,008 patients were analysed. Median IQR age was 42 (31–53) years, diabetes duration 11.8 (6.8–16.0) years, 56.5% men. Median (IQR) HbA1c was 7.9% (7.1–8.8). Microvascular complications were present in 24.4% of patients, 43.6% in those with a diabetes duration >19 years. In presence of known cardiovascular disease 69.3% of patients showed an LDL-C concentration >70 mg/dL, 37% had a systolic blood pressure >135 mmHg and 22.4% were smokers. Conclusions: This study provides a reliable snapshot about the clinical situation of a large population of patients with T1D in Catalonia, which is similar to that of other western areas. The lack of adequate control of cardiovascular risk factors in a significant proportion of patients with cardiovascular disease deserves a more detailed analysis and urges the need for improvement strategies.
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spelling pubmed-80387752021-04-12 Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain) Gimenez-Perez, Gabriel Franch-Nadal, Josep Ortega, Emilio Mata-Cases, Manel Goday, Albert Real, Jordi Rodriguez, Angel Vlacho, Bogdan Mauricio, Dídac J Clin Med Article Background: This study aims to evaluate the clinical characteristics, complications, degree of glycemic control, and cardiovascular risk factor control in patients with type 1 diabetes in Catalonia (Northwest of Spain). Methods: Cross-sectional study using a database including clinical, laboratory, and treatment data. Patients with an ICD10 diagnosis of type 1 diabetes were included, excluding those treated with glucose-lowering agents other than insulin, or treated only with basal insulin two years after diagnosis. Results: 15,008 patients were analysed. Median IQR age was 42 (31–53) years, diabetes duration 11.8 (6.8–16.0) years, 56.5% men. Median (IQR) HbA1c was 7.9% (7.1–8.8). Microvascular complications were present in 24.4% of patients, 43.6% in those with a diabetes duration >19 years. In presence of known cardiovascular disease 69.3% of patients showed an LDL-C concentration >70 mg/dL, 37% had a systolic blood pressure >135 mmHg and 22.4% were smokers. Conclusions: This study provides a reliable snapshot about the clinical situation of a large population of patients with T1D in Catalonia, which is similar to that of other western areas. The lack of adequate control of cardiovascular risk factors in a significant proportion of patients with cardiovascular disease deserves a more detailed analysis and urges the need for improvement strategies. MDPI 2021-04-06 /pmc/articles/PMC8038775/ /pubmed/33917523 http://dx.doi.org/10.3390/jcm10071536 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gimenez-Perez, Gabriel
Franch-Nadal, Josep
Ortega, Emilio
Mata-Cases, Manel
Goday, Albert
Real, Jordi
Rodriguez, Angel
Vlacho, Bogdan
Mauricio, Dídac
Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title_full Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title_fullStr Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title_full_unstemmed Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title_short Clinical Characteristics and Degree of Glycemic and Cardiovascular Risk Factor Control in Patients with Type 1 Diabetes in Catalonia (Spain)
title_sort clinical characteristics and degree of glycemic and cardiovascular risk factor control in patients with type 1 diabetes in catalonia (spain)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038775/
https://www.ncbi.nlm.nih.gov/pubmed/33917523
http://dx.doi.org/10.3390/jcm10071536
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