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α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice

α-Methyl-L-tryptophan (α-MLT) is currently in use as a tracer in its (11)C-labeled form to monitor the health of serotonergic neurons in humans. In the present study, we found this compound to function as an effective weight-loss agent at pharmacological doses in multiple models of obesity in mice....

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Detalles Bibliográficos
Autores principales: Sivaprakasam, Sathish, Ramachandran, Sabarish, Sikder, Mohd Omar Faruk, Bhutia, Yangzom D., Wachtel, Mitchell W., Ganapathy, Vadivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038855/
https://www.ncbi.nlm.nih.gov/pubmed/33720280
http://dx.doi.org/10.1042/BCJ20210100