Cargando…
α-Methyl-l-tryptophan as a weight-loss agent in multiple models of obesity in mice
α-Methyl-L-tryptophan (α-MLT) is currently in use as a tracer in its (11)C-labeled form to monitor the health of serotonergic neurons in humans. In the present study, we found this compound to function as an effective weight-loss agent at pharmacological doses in multiple models of obesity in mice....
Autores principales: | Sivaprakasam, Sathish, Ramachandran, Sabarish, Sikder, Mohd Omar Faruk, Bhutia, Yangzom D., Wachtel, Mitchell W., Ganapathy, Vadivel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038855/ https://www.ncbi.nlm.nih.gov/pubmed/33720280 http://dx.doi.org/10.1042/BCJ20210100 |
Ejemplares similares
-
Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues
por: Mathew, Marilyn, et al.
Publicado: (2023) -
Cell-Surface and Nuclear Receptors in the Colon as Targets for Bacterial Metabolites and Its Relevance to Colon Health
por: Sivaprakasam, Sathish, et al.
Publicado: (2017) -
Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)
por: Bhutia, Yangzom D., et al.
Publicado: (2022) -
Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu
por: Sivaprakasam, Sathish, et al.
Publicado: (2019) -
Pharmacologic inducers of the uric acid exporter ABCG2 as potential drugs for treatment of gouty arthritis
por: Ristic, Bojana, et al.
Publicado: (2020)