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Identification of cell surface targets for CAR-T cell therapies and antibody–drug conjugates in breast cancer
BACKGROUND: Two promising therapeutic strategies in oncology are chimeric antigen receptor-T cell (CAR-T) therapies and antibody–drug conjugates (ADCs). To be effective and safe, these immunotherapies require surface antigens to be sufficiently expressed in tumors and less or not expressed in normal...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038941/ https://www.ncbi.nlm.nih.gov/pubmed/33838601 http://dx.doi.org/10.1016/j.esmoop.2021.100102 |