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Identification of cell surface targets for CAR-T cell therapies and antibody–drug conjugates in breast cancer

BACKGROUND: Two promising therapeutic strategies in oncology are chimeric antigen receptor-T cell (CAR-T) therapies and antibody–drug conjugates (ADCs). To be effective and safe, these immunotherapies require surface antigens to be sufficiently expressed in tumors and less or not expressed in normal...

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Detalles Bibliográficos
Autores principales:	Schettini, F., Barbao, P., Brasó-Maristany, F., Galván, P., Martínez, D., Paré, L., De Placido, S., Prat, A., Guedan, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038941/ https://www.ncbi.nlm.nih.gov/pubmed/33838601 http://dx.doi.org/10.1016/j.esmoop.2021.100102

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