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Structural basis for the DNA-binding activity of human ARID4B Tudor domain

Human ARID4A and ARID4B are homologous proteins that are important in controlling gene expression and epigenetic regulation but have distinct functions. Previous studies have shown that the N-terminal domain of ARID4A is an unusual interdigitated double Tudor domain with DNA-binding activity. Howeve...

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Detalles Bibliográficos
Autores principales:	Ren, Jie, Yao, Hongwei, Hu, Wanhui, Perrett, Sarah, Gong, Weibin, Feng, Yingang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038949/ https://www.ncbi.nlm.nih.gov/pubmed/33675746 http://dx.doi.org/10.1016/j.jbc.2021.100506

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