Dosing Recommendations for Vancomycin in Children and Adolescents with Varying Levels of Obesity and Renal Dysfunction: a Population Pharmacokinetic Study in 1892 Children Aged 1–18 Years

Vancomycin is an effective but potentially nephrotoxic antibiotic commonly used for severe infections. Dosing guidelines for vancomycin in obese children and adolescents with or without renal impairment are currently lacking. This study describes the pharmacokinetics of vancomycin in a large pediatr...

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Detalles Bibliográficos
Autores principales: Smit, Cornelis, Goulooze, Sebastiaan C., Brüggemann, Roger J. M., Sherwin, Catherine M., Knibbe, Catherijne A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038958/
https://www.ncbi.nlm.nih.gov/pubmed/33839974
http://dx.doi.org/10.1208/s12248-021-00577-x

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