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Kidney inflammaging is promoted by CCR2(+) macrophages and tissue-derived micro-environmental factors
The incidence of disorders associated with low inflammatory state, such as chronic kidney disease, increases in the elderly. The accumulation of senescent cells during aging and the senescence-associated secretory phenotype, which leads to inflammaging, is known to be deleterious and account for pro...
Autores principales: | Lefèvre, Lise, Iacovoni, Jason S., Martini, Hélène, Bellière, Julie, Maggiorani, Damien, Dutaur, Marianne, Marsal, Dimitri J., Decaunes, Pauline, Pizzinat, Nathalie, Mialet-Perez, Jeanne, Cussac, Daniel, Parini, Angelo, Douin-Echinard, Victorine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8038964/ https://www.ncbi.nlm.nih.gov/pubmed/33313981 http://dx.doi.org/10.1007/s00018-020-03719-0 |
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