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Inhibition of JAK-STAT Signaling Pathway Alleviates Age-Related Phenotypes in Tendon Stem/Progenitor Cells
Diminished regeneration or healing capacity of tendon occurs during aging. It has been well demonstrated that tendon stem/progenitor cells (TSPCs) play a vital role in tendon maintenance and repair. Here, we identified an accumulation of senescent TSPCs in tendon tissue with aging. In aged TSPCs, th...
Autores principales: | Chen, Minhao, Xiao, Longfei, Dai, Guangchun, Lu, Panpan, Zhang, Yuanwei, Li, Yingjuan, Ni, Ming, Rui, Yunfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039155/ https://www.ncbi.nlm.nih.gov/pubmed/33855026 http://dx.doi.org/10.3389/fcell.2021.650250 |
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