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Perspectives on High-Throughput Ligand/Protein Docking With Martini MD Simulations
Molecular docking is central to rational drug design. Current docking techniques suffer, however, from limitations in protein flexibility and solvation models and by the use of simplified scoring functions. All-atom molecular dynamics simulations, on the other hand, feature a realistic representatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039319/ https://www.ncbi.nlm.nih.gov/pubmed/33855050 http://dx.doi.org/10.3389/fmolb.2021.657222 |