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The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease

BACKGROUND: We aimed to evaluate a potential link between colonization of gingival crevices by the Entamoeba gingivalis as oral parasite microbiome and Hepatitis B infection among gum disease Sudanese patients. METHODS: This study was conducted on 448 gum disease patients attending to Dental Clinic...

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Autores principales: TAMOMH, Abdelhakam G., SULIMAN, Mohammed A., YOUSIF, Sabah R., LIU, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039478/
https://www.ncbi.nlm.nih.gov/pubmed/33884018
http://dx.doi.org/10.18502/ijpa.v15i4.4874
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author TAMOMH, Abdelhakam G.
SULIMAN, Mohammed A.
YOUSIF, Sabah R.
LIU, Hui
author_facet TAMOMH, Abdelhakam G.
SULIMAN, Mohammed A.
YOUSIF, Sabah R.
LIU, Hui
author_sort TAMOMH, Abdelhakam G.
collection PubMed
description BACKGROUND: We aimed to evaluate a potential link between colonization of gingival crevices by the Entamoeba gingivalis as oral parasite microbiome and Hepatitis B infection among gum disease Sudanese patients. METHODS: This study was conducted on 448 gum disease patients attending to Dental Clinic of Kosti Teaching Hospital, Kosti, Sudan in 2017–2018. Oral symptoms were registered in 336 patients at different stages of the HBV infection and in 112 HBV seronegative gum disease control. All participants were screened for HBV using ELISA test. Unstimulated whole saliva and gingival scraping were obtained and analyzed for the presence of the amoeba using a parasitological technique. RESULTS: Statistically highly significant correlation was found between the detection of the E. gingivalis in Saliva/gingival scraping and gum illness disease with HBV-infected patients than healthy control group (P<0.05). There was high association between the occurrence of the amoeba between the two groups and smoking, snuffing habitats (P<0.05), inversely, no association with the oral personal hygiene. CONCLUSION: The presence of the amoeba was not related to the degree of gum diseases only, but to the HBV infection diagnosis. To our knowledge, this is the first study of E. gingivalis in association with HBV infection among gum disease Sudanese patients; maybe predict the role of oral parasitic microbiome in the status of gum disease in HBV infection.
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spelling pubmed-80394782021-04-20 The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease TAMOMH, Abdelhakam G. SULIMAN, Mohammed A. YOUSIF, Sabah R. LIU, Hui Iran J Parasitol Short Communication BACKGROUND: We aimed to evaluate a potential link between colonization of gingival crevices by the Entamoeba gingivalis as oral parasite microbiome and Hepatitis B infection among gum disease Sudanese patients. METHODS: This study was conducted on 448 gum disease patients attending to Dental Clinic of Kosti Teaching Hospital, Kosti, Sudan in 2017–2018. Oral symptoms were registered in 336 patients at different stages of the HBV infection and in 112 HBV seronegative gum disease control. All participants were screened for HBV using ELISA test. Unstimulated whole saliva and gingival scraping were obtained and analyzed for the presence of the amoeba using a parasitological technique. RESULTS: Statistically highly significant correlation was found between the detection of the E. gingivalis in Saliva/gingival scraping and gum illness disease with HBV-infected patients than healthy control group (P<0.05). There was high association between the occurrence of the amoeba between the two groups and smoking, snuffing habitats (P<0.05), inversely, no association with the oral personal hygiene. CONCLUSION: The presence of the amoeba was not related to the degree of gum diseases only, but to the HBV infection diagnosis. To our knowledge, this is the first study of E. gingivalis in association with HBV infection among gum disease Sudanese patients; maybe predict the role of oral parasitic microbiome in the status of gum disease in HBV infection. Tehran University of Medical Sciences 2020 /pmc/articles/PMC8039478/ /pubmed/33884018 http://dx.doi.org/10.18502/ijpa.v15i4.4874 Text en Copyright © 2020 Tamomh et al. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Short Communication
TAMOMH, Abdelhakam G.
SULIMAN, Mohammed A.
YOUSIF, Sabah R.
LIU, Hui
The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title_full The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title_fullStr The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title_full_unstemmed The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title_short The Oral Parasitic Microbiome in Hepatitis B Virus Infected Sudanese Patients with Gum Disease
title_sort oral parasitic microbiome in hepatitis b virus infected sudanese patients with gum disease
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039478/
https://www.ncbi.nlm.nih.gov/pubmed/33884018
http://dx.doi.org/10.18502/ijpa.v15i4.4874
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