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Dissecting the role of glutamine in seeding peptide aggregation
Poly glutamine and glutamine-rich peptides play a central role in a plethora of pathological aggregation events. However, biophysical characterization of soluble oligomers -the most toxic species involved in these processes- remains elusive due to their structural heterogeneity and dynamical nature....
Autores principales: | Barrera, Exequiel E., Zonta, Francesco, Pantano, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039506/ https://www.ncbi.nlm.nih.gov/pubmed/33868596 http://dx.doi.org/10.1016/j.csbj.2021.02.014 |
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