Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro

The disease-initiating molecular events for age-related macular degeneration (AMD), a multifactorial retinal disease affecting many millions of elderly individuals worldwide, are still unknown. Of the over 30 risk and protective loci so far associated with AMD through whole genome-wide association s...

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Detalles Bibliográficos
Autores principales: Pan, Yang, Iejima, Daisuke, Nakayama, Mao, Suga, Akiko, Noda, Toru, Kaur, Inderjeet, Das, Taraprasad, Chakrabarti, Subhabrata, Guymer, Robyn H., DeAngelis, Margaret M., Yamamoto, Megumi, Baird, Paul N., Iwata, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039566/
https://www.ncbi.nlm.nih.gov/pubmed/33636181
http://dx.doi.org/10.1016/j.jbc.2021.100456

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