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Omidenepag, a Selective, Prostanoid EP2 Agonist, Does Not Suppress Adipogenesis in 3D Organoids of Human Orbital Fibroblasts

PURPOSE: The purpose of this study was to present the effects of the prostanoid EP2 agonist, omidenepag (OMD) on human orbital fibroblasts (HOFs) using a three-dimension (3D) cell culture. METHODS: During adipogenesis of 3D HOFs organoids, changes in size, lipids staining, mRNA expression of adipoge...

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Detalles Bibliográficos
Autores principales: Hikage, Fumihito, Ida, Yosuke, Ouchi, Yuika, Watanabe, Megumi, Ohguro, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039573/
https://www.ncbi.nlm.nih.gov/pubmed/34003984
http://dx.doi.org/10.1167/tvst.10.4.6