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Angiotensin II-mediated improvement of renal mitochondrial function via the AMPK/PGC-1α/NRF-2 pathway is superior to norepinephrine in a rat model of septic shock associated with acute renal injury

BACKGROUND: This study sought to compare the therapeutic effects of angiotensin II (ANG II) and norepinephrine (NE) on cecal ligation and puncture (CLP)-induced septic acute kidney injury (AKI) in rats. METHODS: Sepsis shock was induced in anesthesia Sprague-Dawley male rats by CLP model for 24 hour...

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Detalles Bibliográficos
Autores principales:	An, Hui, Hu, Zhenjie, Chen, Yuhong, Cheng, Lianfang, Shi, Jian, Han, Linan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039700/ https://www.ncbi.nlm.nih.gov/pubmed/33850878 http://dx.doi.org/10.21037/atm-21-621

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