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Role of Endoscopy in Primary Sclerosing Cholangitis
Primary sclerosing cholangitis (PSC) is a progressive disease of the bile ducts that usually results in chronic liver disease often requiring liver transplantation. Endoscopy remains crucial to the care of these patients, although magnetic resonance cholangiopancreatography has replaced endoscopic r...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Korean Society of Gastrointestinal Endoscopy
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039754/ https://www.ncbi.nlm.nih.gov/pubmed/32380796 http://dx.doi.org/10.5946/ce.2020.019-IDEN |
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author | Bhat, Purnima Aabakken, Lars |
author_facet | Bhat, Purnima Aabakken, Lars |
author_sort | Bhat, Purnima |
collection | PubMed |
description | Primary sclerosing cholangitis (PSC) is a progressive disease of the bile ducts that usually results in chronic liver disease often requiring liver transplantation. Endoscopy remains crucial to the care of these patients, although magnetic resonance cholangiopancreatography has replaced endoscopic retrograde cholangiopancreatography (ERCP) as the primary imaging modality for diagnosis. For detection of dysplasia or cholangiocarcinoma, ERCP with intraductal sampling remains compulsory. Moreover, dominant strictures play an important part in the disease development, and management by balloon dilatation or stenting could contribute to long-term prognosis. In addition, endoscopy offers management for adverse events such as bile leaks and anastomotic strictures after liver transplantation. Finally, the special phenotype of inflammatory bowel disease associated with PSC as well as the frequent occurrence of portal hypertension mandates close follow-up with colonoscopy and upper endoscopy. With the emergence of novel techniques, the endoscopist remains a key member of the multidisciplinary team caring for PSC patients. |
format | Online Article Text |
id | pubmed-8039754 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | MEDLINE/PubMed |
spelling | pubmed-80397542021-04-19 Role of Endoscopy in Primary Sclerosing Cholangitis Bhat, Purnima Aabakken, Lars Clin Endosc Review Primary sclerosing cholangitis (PSC) is a progressive disease of the bile ducts that usually results in chronic liver disease often requiring liver transplantation. Endoscopy remains crucial to the care of these patients, although magnetic resonance cholangiopancreatography has replaced endoscopic retrograde cholangiopancreatography (ERCP) as the primary imaging modality for diagnosis. For detection of dysplasia or cholangiocarcinoma, ERCP with intraductal sampling remains compulsory. Moreover, dominant strictures play an important part in the disease development, and management by balloon dilatation or stenting could contribute to long-term prognosis. In addition, endoscopy offers management for adverse events such as bile leaks and anastomotic strictures after liver transplantation. Finally, the special phenotype of inflammatory bowel disease associated with PSC as well as the frequent occurrence of portal hypertension mandates close follow-up with colonoscopy and upper endoscopy. With the emergence of novel techniques, the endoscopist remains a key member of the multidisciplinary team caring for PSC patients. Korean Society of Gastrointestinal Endoscopy 2021-03 2020-05-08 /pmc/articles/PMC8039754/ /pubmed/32380796 http://dx.doi.org/10.5946/ce.2020.019-IDEN Text en Copyright © 2021 Korean Society of Gastrointestinal Endoscopy https://creativecommons.org/licenses/by-nc/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Bhat, Purnima Aabakken, Lars Role of Endoscopy in Primary Sclerosing Cholangitis |
title | Role of Endoscopy in Primary Sclerosing Cholangitis |
title_full | Role of Endoscopy in Primary Sclerosing Cholangitis |
title_fullStr | Role of Endoscopy in Primary Sclerosing Cholangitis |
title_full_unstemmed | Role of Endoscopy in Primary Sclerosing Cholangitis |
title_short | Role of Endoscopy in Primary Sclerosing Cholangitis |
title_sort | role of endoscopy in primary sclerosing cholangitis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039754/ https://www.ncbi.nlm.nih.gov/pubmed/32380796 http://dx.doi.org/10.5946/ce.2020.019-IDEN |
work_keys_str_mv | AT bhatpurnima roleofendoscopyinprimarysclerosingcholangitis AT aabakkenlars roleofendoscopyinprimarysclerosingcholangitis |