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Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome

BACKGROUND: How the surgical stabilization of rib fractures after trauma affects the development of acute respiratory distress syndrome and impacts survival has yet to be determined in a large database. We hypothesized that surgical stabilization of rib fractures would not decrease the incidence of...

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Autores principales: Taghavi, Sharven, Ali, Ayman, Green, Erik, Schmitt, Kyle, Jackson-Weaver, Olan, Tatum, Danielle, Harris, Charles, Guidry, Chrissy, McGrew, Patrick, Schroll, Rebecca, Kolls, Jay, Duchesne, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039755/
https://www.ncbi.nlm.nih.gov/pubmed/33461776
http://dx.doi.org/10.1016/j.surg.2020.12.010
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author Taghavi, Sharven
Ali, Ayman
Green, Erik
Schmitt, Kyle
Jackson-Weaver, Olan
Tatum, Danielle
Harris, Charles
Guidry, Chrissy
McGrew, Patrick
Schroll, Rebecca
Kolls, Jay
Duchesne, Juan
author_facet Taghavi, Sharven
Ali, Ayman
Green, Erik
Schmitt, Kyle
Jackson-Weaver, Olan
Tatum, Danielle
Harris, Charles
Guidry, Chrissy
McGrew, Patrick
Schroll, Rebecca
Kolls, Jay
Duchesne, Juan
author_sort Taghavi, Sharven
collection PubMed
description BACKGROUND: How the surgical stabilization of rib fractures after trauma affects the development of acute respiratory distress syndrome and impacts survival has yet to be determined in a large database. We hypothesized that surgical stabilization of rib fractures would not decrease the incidence of acute respiratory distress syndrome. METHODS: The National Trauma Data Bank was queried for all traumatic rib fractures in 2016. Patients were divided into groups with single rib fractures, multiple rib fractures, and flail chest. Nonoperative therapy was compared with stabilization of rib fractures of 1 to 2 ribs or 3+ ribs. RESULTS: There were 114,972 total patients with rib fractures meeting inclusion criteria, with 5,106 (4.4%) having flail chest, 24,726 (21.5%) having single rib fractures, and 85,140 (74.1%) having multiple rib fractures. Those with flail chest (15.9%) were most likely to get rib plating in comparison to multiple rib fractures (0.9%) and single rib fractures (0.2%); P < .001. On logistic regression, surgical stabilization of rib fractures 1 to 2 ribs (odds ratio: 0.17, 95% confidence interval: 0.10–0.28) or 3+ ribs (odds ratio: 0.17, 95% confidence interval: 0.11–0.28), with nonoperative therapy as the reference was associated with survival. Variables associated with mortality included increasing age, male sex, increasing injury severity score, decreased Glasgow coma scale, requirement of transfusions, and hypotension on admission. Surgical stabilization of rib fractures 3+ ribs (odds ratio: 2.30, 95% confidence interval: 1.58–3.37) was associated with acute respiratory distress syndrome but not 1 to 2 ribs (odd ratio: 1.55, 95% confidence interval: 0.97–2.48). On logistic regression of only patients with flail chest, stabilization of rib fractures was associated with decreased mortality but not increased risk of acute respiratory distress syndrome. CONCLUSION: The increased risk of acute respiratory distress syndrome should be considered in the preoperative assessment for stabilization of rib fractures.
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spelling pubmed-80397552021-04-12 Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome Taghavi, Sharven Ali, Ayman Green, Erik Schmitt, Kyle Jackson-Weaver, Olan Tatum, Danielle Harris, Charles Guidry, Chrissy McGrew, Patrick Schroll, Rebecca Kolls, Jay Duchesne, Juan Surgery Trauma/Critical Care BACKGROUND: How the surgical stabilization of rib fractures after trauma affects the development of acute respiratory distress syndrome and impacts survival has yet to be determined in a large database. We hypothesized that surgical stabilization of rib fractures would not decrease the incidence of acute respiratory distress syndrome. METHODS: The National Trauma Data Bank was queried for all traumatic rib fractures in 2016. Patients were divided into groups with single rib fractures, multiple rib fractures, and flail chest. Nonoperative therapy was compared with stabilization of rib fractures of 1 to 2 ribs or 3+ ribs. RESULTS: There were 114,972 total patients with rib fractures meeting inclusion criteria, with 5,106 (4.4%) having flail chest, 24,726 (21.5%) having single rib fractures, and 85,140 (74.1%) having multiple rib fractures. Those with flail chest (15.9%) were most likely to get rib plating in comparison to multiple rib fractures (0.9%) and single rib fractures (0.2%); P < .001. On logistic regression, surgical stabilization of rib fractures 1 to 2 ribs (odds ratio: 0.17, 95% confidence interval: 0.10–0.28) or 3+ ribs (odds ratio: 0.17, 95% confidence interval: 0.11–0.28), with nonoperative therapy as the reference was associated with survival. Variables associated with mortality included increasing age, male sex, increasing injury severity score, decreased Glasgow coma scale, requirement of transfusions, and hypotension on admission. Surgical stabilization of rib fractures 3+ ribs (odds ratio: 2.30, 95% confidence interval: 1.58–3.37) was associated with acute respiratory distress syndrome but not 1 to 2 ribs (odd ratio: 1.55, 95% confidence interval: 0.97–2.48). On logistic regression of only patients with flail chest, stabilization of rib fractures was associated with decreased mortality but not increased risk of acute respiratory distress syndrome. CONCLUSION: The increased risk of acute respiratory distress syndrome should be considered in the preoperative assessment for stabilization of rib fractures. Elsevier Inc. 2021-06 2020-12-19 /pmc/articles/PMC8039755/ /pubmed/33461776 http://dx.doi.org/10.1016/j.surg.2020.12.010 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Trauma/Critical Care
Taghavi, Sharven
Ali, Ayman
Green, Erik
Schmitt, Kyle
Jackson-Weaver, Olan
Tatum, Danielle
Harris, Charles
Guidry, Chrissy
McGrew, Patrick
Schroll, Rebecca
Kolls, Jay
Duchesne, Juan
Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title_full Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title_fullStr Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title_full_unstemmed Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title_short Surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
title_sort surgical stabilization of rib fractures is associated with improved survival but increased acute respiratory distress syndrome
topic Trauma/Critical Care
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039755/
https://www.ncbi.nlm.nih.gov/pubmed/33461776
http://dx.doi.org/10.1016/j.surg.2020.12.010
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