Clinical course in two children with Juvenile Paget's disease during long-term treatment with intravenous bisphosphonates

Juvenile Paget disease (JPD) is an ultra-rare disease, characterized by loss of function of osteoprotegerin. Osteoprotegerin inhibits osteoclast activation via the receptor activator of nuclear factor κB (RANK) pathway. Severely affected children suffer from bone deformities and pain and require lon...

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Detalles Bibliográficos
Autores principales: Höppner, Jakob, Steff, Katja, Misof, Barbara M., Schündeln, Michael M., Hövel, Matthias, Lücke, Thomas, Grasemann, Corinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039828/
https://www.ncbi.nlm.nih.gov/pubmed/33850973
http://dx.doi.org/10.1016/j.bonr.2021.100762

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