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CD45RO(-)CD8(+) T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis

Rationale: Estrogen-dependent cancers (e.g., breast, endometrial, and ovarian cancers) are among the leading causes of morbidity and mortality in women worldwide. Recently, exosomes released by tumor-infiltrating CD8(+) T cells have been under the spotlight in the field of cancer immunotherapy. Our...

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Detalles Bibliográficos
Autores principales: Zhou, Wen-Jie, Zhang, Jie, Xie, Feng, Wu, Jiang-Nan, Ye, Jiang-Feng, Wang, Jian, Wu, Ke, Li, Ming-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039953/
https://www.ncbi.nlm.nih.gov/pubmed/33859750
http://dx.doi.org/10.7150/thno.58337