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CD45RO(-)CD8(+) T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis
Rationale: Estrogen-dependent cancers (e.g., breast, endometrial, and ovarian cancers) are among the leading causes of morbidity and mortality in women worldwide. Recently, exosomes released by tumor-infiltrating CD8(+) T cells have been under the spotlight in the field of cancer immunotherapy. Our...
Autores principales: | Zhou, Wen-Jie, Zhang, Jie, Xie, Feng, Wu, Jiang-Nan, Ye, Jiang-Feng, Wang, Jian, Wu, Ke, Li, Ming-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8039953/ https://www.ncbi.nlm.nih.gov/pubmed/33859750 http://dx.doi.org/10.7150/thno.58337 |
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