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DPP-4 Inhibitors Have Different Effects on Endothelial Low-Grade Inflammation and on the M1-M2 Macrophage Polarization Under Hyperglycemic Conditions

PURPOSE: We explored the anti-inflammatory role of the DPP-4 inhibitor teneligliptin, using sitagliptin as comparator, in different in vitro models of low-grade inflammation (LGI), evaluating the hyperglycemia-induced endothelial inflammation, the macrophage polarization, and the endothelium–macroph...

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Detalles Bibliográficos
Autores principales: De Nigris, Valeria, Prattichizzo, Francesco, Iijima, Hiroaki, Ceriello, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040089/
https://www.ncbi.nlm.nih.gov/pubmed/33854350
http://dx.doi.org/10.2147/DMSO.S302621

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