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Reference-free transcriptome signatures for prostate cancer prognosis

BACKGROUND: RNA-seq data are increasingly used to derive prognostic signatures for cancer outcome prediction. A limitation of current predictors is their reliance on reference gene annotations, which amounts to ignoring large numbers of non-canonical RNAs produced in disease tissues. A recently intr...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha T.N., Xue, Haoliang, Firlej, Virginie, Ponty, Yann, Gallopin, Melina, Gautheret, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040209/
https://www.ncbi.nlm.nih.gov/pubmed/33845808
http://dx.doi.org/10.1186/s12885-021-08021-1