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Analysis of the heterogeneity of the BCR H-CDR3 repertoire in the bone marrow and spleen of 3-, 12-, and 20-month old mice

The number of central and peripheral B cells and their responsiveness are decreased in aged mice. The diversity of mice central and peripheral B cell repertoires with increasing age has not been elucidated. In this study, we demonstrated that there were significant differences in the usage of some V...

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Detalles Bibliográficos
Autores principales:	Ma, Lina, Tao, Xinxin, He, Xiaoyan, Wang, Peng, Ma, Long, Shi, Bin, Yao, Xinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040230/ https://www.ncbi.nlm.nih.gov/pubmed/33845848 http://dx.doi.org/10.1186/s12979-021-00231-2

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