Identification of low-dose radiation-induced exosomal circ-METRN and miR-4709-3p/GRB14/PDGFRα pathway as a key regulatory mechanism in Glioblastoma progression and radioresistance: Functional validation and clinical theranostic significance

Glioblastoma is a central nervous malignancy with a very poor prognosis. This study attempted to explore the role of exosomes induced by low-dose radiation-induced (ldrEXOs) and ldrEXOs-derived circ-METRN in glioblastoma progression and radioresistance at the molecular, cellular, animal, and clinica...

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Detalles Bibliográficos
Autores principales: Wang, Xinxin, Cao, Qinchen, Shi, Yonggang, Wu, Xiaolong, Mi, Yin, Liu, Ke, Kan, Quancheng, Fan, Ruitai, Liu, Zhangsuo, Zhang, Mingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040305/
https://www.ncbi.nlm.nih.gov/pubmed/33867829
http://dx.doi.org/10.7150/ijbs.57168

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