Cargando…
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway
Spinal cord injury (SCI) results in a wide range of disabilities. Its complex pathophysiological process limits the effectiveness of many clinical treatments. Betulinic acid (BA) has been shown to be an effective treatment for some neurological diseases, but it has not been studied in SCI. In this s...
Autores principales: | Wu, Chenyu, Chen, Huanwen, Zhuang, Rong, Zhang, Haojie, Wang, Yongli, Hu, Xinli, Xu, Yu, Li, Jiafeng, Li, Yao, Wang, Xiangyang, Xu, Hui, Ni, Wenfei, Zhou, Kailiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040310/ https://www.ncbi.nlm.nih.gov/pubmed/33867836 http://dx.doi.org/10.7150/ijbs.57825 |
Ejemplares similares
-
Metformin Promotes the Survival of Random-Pattern Skin Flaps by Inducing Autophagy via the AMPK-mTOR-TFEB signaling pathway
por: Wu, Hongqiang, et al.
Publicado: (2019) -
Role of Pyroptosis in Traumatic Brain and Spinal Cord Injuries
por: Hu, Xinli, et al.
Publicado: (2020) -
Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement
por: Wu, Chenyu, et al.
Publicado: (2020) -
Trehalose Augments Neuron Survival and Improves Recovery from Spinal Cord Injury via mTOR-Independent Activation of Autophagy
por: Zhou, Kailiang, et al.
Publicado: (2021) -
AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR
por: Collodet, Caterina, et al.
Publicado: (2019)