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MicroRNA-223 restricts liver fibrosis by inhibiting the TAZ-IHH-GLI2 and PDGF signaling pathways via the crosstalk of multiple liver cell types

Background & Aims: Liver fibrosis is a common consequence of chronic liver injury and is characterized by the accumulation of extracellular matrix mainly generated from activated hepatic stellate cells (HSCs). At present, the mechanisms underlying liver fibrogenesis remain obscure and effective...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolin, Seo, Wonhyo, Park, Seol Hee, Fu, Yaojie, Hwang, Seonghwan, Rodrigues, Robim M., Feng, Dechun, Gao, Bin, He, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040312/
https://www.ncbi.nlm.nih.gov/pubmed/33867837
http://dx.doi.org/10.7150/ijbs.58365