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Increased nuclear translation of YAP might act as a potential therapeutic target for NF1-related plexiform neurofibroma
Plexiform neurofibroma (pNF) in the head and neck is a characteristic feature in patients with neurofibromatosis type 1 (NF1) and is associated with significant disfigurement and psychological distress. Yes-associated protein (YAP), the key molecule involved in the Hippo pathway, is a vital transduc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040406/ https://www.ncbi.nlm.nih.gov/pubmed/33850471 http://dx.doi.org/10.7150/ijms.52431 |