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Increased nuclear translation of YAP might act as a potential therapeutic target for NF1-related plexiform neurofibroma

Plexiform neurofibroma (pNF) in the head and neck is a characteristic feature in patients with neurofibromatosis type 1 (NF1) and is associated with significant disfigurement and psychological distress. Yes-associated protein (YAP), the key molecule involved in the Hippo pathway, is a vital transduc...

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Detalles Bibliográficos
Autores principales: Liu, Jia-Liang, You, Yuan-He, Tian, Zhuo-Wei, Xiao, Meng, Zheng, Jia-Wei, Wang, Yan-An, Du, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040406/
https://www.ncbi.nlm.nih.gov/pubmed/33850471
http://dx.doi.org/10.7150/ijms.52431