SARS-CoV-2-Induced Severe Immune Thrombocytopenic Purpura

Hematologic changes are common in coronavirus infections, including lymphopenia and thrombocytopenia. Thrombocytopenia was frequent during the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 - 2003. The mechanisms involved in platelet deficiency are unclear. Many viruses are known t...

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Detalles Bibliográficos
Autores principales: Gonze, Aurelien, Hannesse, Colin, Coppens, Nathalie, Vellemans, Helene, Maury, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040431/
https://www.ncbi.nlm.nih.gov/pubmed/33984082
http://dx.doi.org/10.14740/jmc3481
Descripción
Sumario:Hematologic changes are common in coronavirus infections, including lymphopenia and thrombocytopenia. Thrombocytopenia was frequent during the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 - 2003. The mechanisms involved in platelet deficiency are unclear. Many viruses are known to trigger immune thrombocytopenic purpura (ITP), but the disease is rarely described in association with coronavirus. We describe the case of acute ITP associated with coronavirus disease 19 (COVID-19) in an 86-year-old woman. Intravenous gamma-globulin and corticosteroids were effective on platelet count evolution.

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