Cargando…

3,3'-Diindolylmethane induces gastric cancer cells death via STIM1 mediated store-operated calcium entry

3,3'-Diindolylmethane (DIM), a natural phytochemicals isolated from cruciferous vegetables, has been reported to inhibit human gastric cancer cells proliferation and induce cells apoptosis as well as autophagy, but its mechanisms are still unclear. Store-operated calcium entry (SOCE) is a main...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Yang, Li, Xue, Wang, Zhihua, Ye, Fen, Xu, Wenrong, Lu, Rongzhu, Shen, Haijun, Miao, Shuhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040462/ https://www.ncbi.nlm.nih.gov/pubmed/33867841 http://dx.doi.org/10.7150/ijbs.56833

Ejemplares similares

STIM and Orai1 Variants in Store-Operated Calcium Entry
por: Rosado, Juan A., et al.
Publicado: (2016)

Differential Roles for STIM1 and STIM2 in Store-Operated Calcium Entry in Rat Neurons
por: Gruszczynska-Biegala, Joanna, et al.
Publicado: (2011)

Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry
por: Walsh, Ciara M., et al.
Publicado: (2009)

Initial activation of STIM1, the regulator of store-operated calcium entry
por: Zhou, Yubin, et al.
Publicado: (2013)

Evidence for an interaction between Golli and STIM1 in store-operated calcium entry
por: Walsh, Ciara M., et al.
Publicado: (2010)

A STIM2 splice variant negatively regulates store-operated calcium entry
por: Miederer, Anna-Maria, et al.
Publicado: (2015)

Orai1 and Orai3 in Combination with Stim1 Mediate the Majority of Store-operated Calcium Entry in Astrocytes
por: Kwon, Jea, et al.
Publicado: (2017)

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry
por: Stathopulos, Peter B., et al.
Publicado: (2013)

Dynamic interaction of SARAF with STIM1 and Orai1 to modulate store-operated calcium entry
por: Albarran, Letizia, et al.
Publicado: (2016)

NEUROD2 Regulates Stim1 Expression and Store-Operated Calcium Entry in Cortical Neurons
por: Guner, Gokhan, et al.
Publicado: (2017)

Orai1, 2, 3 and STIM1 promote store-operated calcium entry in pulmonary arterial smooth muscle cells
por: Wang, Jian, et al.
Publicado: (2017)

Association of the IP3R to STIM1 provides a reduced intraluminal calcium microenvironment, resulting in enhanced store-operated calcium entry
por: Sampieri, Alicia, et al.
Publicado: (2018)

AMPA Receptors Are Involved in Store-Operated Calcium Entry and Interact with STIM Proteins in Rat Primary Cortical Neurons
por: Gruszczynska-Biegala, Joanna, et al.
Publicado: (2016)

Store-Operated Calcium Entry via STIM1 Contributes to MRGPRX2 Induced Mast Cell Functions
por: Occhiuto, Christopher J., et al.
Publicado: (2020)

The KSR2-calcineurin complex regulates STIM1-ORAI1 dynamics and store-operated calcium entry (SOCE)
por: Giurisato, E., et al.
Publicado: (2014)

Store-operated calcium entry and the localization of STIM1 and Orai1 proteins in isolated mouse sinoatrial node cells
por: Liu, Jie, et al.
Publicado: (2015)

Store-Operated Calcium Entry in Breast Cancer Cells Is Insensitive to Orai1 and STIM1 N-Linked Glycosylation
por: Sanchez-Collado, Jose, et al.
Publicado: (2022)

Increased store-operated Ca(2+) entry mediated by GNB5 and STIM1
por: Kang, Namju, et al.
Publicado: (2018)

Regulation of store-operated calcium entry
por: Kodakandla, Goutham, et al.
Publicado: (2023)

3,3′-Diindolylmethane: A Promising Sensitizer of γ-Irradiation
por: Wang, Wenjing, et al.
Publicado: (2015)

Cellular and Molecular Mechanisms of 3,3′-Diindolylmethane in Gastrointestinal Cancer
por: Kim, Soo Mi
Publicado: (2016)

3,3’-Diindolylmethane induces apoptosis and autophagy in fission yeast
por: Emami, Parvaneh, et al.
Publicado: (2021)

Anti-Cancer Effects of 3, 3’-Diindolylmethane on Human Hepatocellular Carcinoma Cells Is Enhanced by Calcium Ionophore: The Role of Cytosolic Ca(2+) and p38 MAPK
por: Jiang, Yuanyue, et al.
Publicado: (2019)

The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration
por: Hong, Junmou, et al.
Publicado: (2019)

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines
por: Zheng, Sisi, et al.
Publicado: (2018)

EB1 traps STIM1 and regulates local store-operated Ca(2+) entry
por: Wang, Qiao-Chu, et al.
Publicado: (2018)

Interplay between ER Ca(2+) Binding Proteins, STIM1 and STIM2, Is Required for Store-Operated Ca(2+) Entry
por: Nelson, Heather A., et al.
Publicado: (2018)

Interactions between β-Lactoglobulin and 3,3′-Diindolylmethane in Model System
por: Wang, Cuina, et al.
Publicado: (2019)

Amelioration of Hyperglycemia-Induced Nephropathy by 3,3′-Diindolylmethane in Diabetic Mice
por: Choi, Kyeong-Mi, et al.
Publicado: (2019)

Activation and regulation of store-operated calcium entry
por: Smyth, Jeremy T, et al.
Publicado: (2010)

The heterogeneity of store-operated calcium entry in melanoma
por: Hooper, Robert, et al.
Publicado: (2016)

Mutant IP(3) receptors attenuate store-operated Ca(2+) entry by destabilizing STIM–Orai interactions in Drosophila neurons
por: Chakraborty, Sumita, et al.
Publicado: (2016)

Retrograde regulation of STIM1-Orai1 interaction and store-operated Ca(2+) entry by calsequestrin
por: Wang, Limin, et al.
Publicado: (2015)

Defective STIM-mediated store operated Ca(2+) entry in hepatocytes leads to metabolic dysfunction in obesity
por: Arruda, Ana Paula, et al.
Publicado: (2017)

A homozygous STIM1 mutation impairs store-operated calcium entry and natural killer cell effector function without clinical immunodeficiency
por: Parry, David A., et al.
Publicado: (2016)

Correction: The deregulation of STIM1 and store operative calcium entry (SOCE) impaired aortic smooth muscle cells contractility in aortic medial degeneration
Publicado: (2020)

Resveratrol sensitizes A549 cells to irradiation damage via suppression of store-operated calcium entry with Orai1 and STIM1 downregulation
por: Lele, Wu, et al.
Publicado: (2021)

Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels
por: Rana, Anshul, et al.
Publicado: (2015)

STIM1 Protein Activates Store-Operated Calcium Channels in Cellular Model of Huntington’s Disease
por: Vigont, V. A., et al.
Publicado: (2014)

Very Low-Density Lipoproteins of Metabolic Syndrome Modulates STIM1, Suppresses Store-Operated Calcium Entry, and Deranges Myofilament Proteins in Atrial Myocytes
por: Shiou, Yi-Lin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1vdi9dn6prf3r3tvbc11vd3csl