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MnSOD Lysine 68 acetylation leads to cisplatin and doxorubicin resistance due to aberrant mitochondrial metabolism
Manganese superoxide dismutase (MnSOD) acetylation (Ac) has been shown to be a key post-translational modification important in the regulation of detoxification activity in various disease models. We have previously demonstrated that MnSOD lysine-68 (K68) acetylation (K68-Ac) leads to a change in fu...
Autores principales: | Gao, Yucheng, Zhu, Yueming, Tran, Elizabeth L., Tokars, Valerie, Dean, Angela E., Quan, Songhua, Gius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040469/ https://www.ncbi.nlm.nih.gov/pubmed/33867840 http://dx.doi.org/10.7150/ijbs.51184 |
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