Aurka deficiency in the intestinal epithelium promotes age-induced obesity via propionate-mediated AKT activation

Aurora-A kinase, a serine/threonine mitotic kinase involved in mitosis, is overexpressed in several human cancers. A recent study showed that Aurora-A mediates glucose metabolism via SOX8/FOXK1 in ovarian cancer. However, the roles of Aurora-A in metabolic diseases remain unclear. This study found t...

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Detalles Bibliográficos
Autores principales: Sun, Na, Meng, Fandong, Zhao, Jie, Li, Xueqin, Li, Rongqing, Han, Jing, Chen, Xin, Cheng, Wanpeng, Yang, Xiaoying, Kou, Yanbo, Zheng, Kuiyang, Yang, Jing, Ikezoe, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040479/
https://www.ncbi.nlm.nih.gov/pubmed/33867847
http://dx.doi.org/10.7150/ijbs.56477

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