Cargando…

Clinical impact of genomic characterization of 15 patients with acute megakaryoblastic leukemia–related malignancies

Acute megakaryoblastic leukemia (AMKL) is a rare subtype of acute myeloid leukemia but is approximately 500 times more likely to develop in children with Down syndrome (DS) through transformation of transient abnormal myelopoiesis (TAM). This study investigates the clinical significance of genomic h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lalonde, Emilie, Rentas, Stefan, Wertheim, Gerald, Cao, Kajia, Surrey, Lea F., Lin, Fumin, Zhao, Xiaonan, Obstfeld, Amrom, Aplenc, Richard, Luo, Minjie, Li, Marilyn M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2021
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040732/ https://www.ncbi.nlm.nih.gov/pubmed/33832921 http://dx.doi.org/10.1101/mcs.a005975

Ejemplares similares

Clinical Impact of Genomic Information in Pediatric Leukemia
por: Lalonde, Emilie, et al.
Publicado: (2017)

Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin
por: Fløisand, Yngvar, et al.
Publicado: (2013)

An Unusual Case of Myeloperoxidase-Positive Acute Megakaryoblastic Leukemia
por: Lee, Hyeyoung, et al.
Publicado: (2015)

Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma
por: Kawasaki, Yukako, et al.
Publicado: (2015)

Genomic Diagnosis for Pediatric Disorders: Revolution and Evolution
por: Lalonde, Emilie, et al.
Publicado: (2020)

Clinical Characteristics and Prognosis of 27 Patients with Childhood Acute Megakaryoblastic Leukemia
por: Qi, Haixiao, et al.
Publicado: (2020)

Acute Megakaryoblastic Leukemia with t(1;22) Mimicking Neuroblastoma in an Infant
por: Gökçe, Müge, et al.
Publicado: (2015)

Coexistence of myelodysplastic syndrome and acute megakaryoblastic leukemia: An aggressive disease
por: Kasinathan, Ganesh, et al.
Publicado: (2021)

Immunophenotypic Analysis of Acute Megakaryoblastic Leukemia: A EuroFlow Study
por: Brouwer, Nienke, et al.
Publicado: (2022)

Therapy-Related Acute Megakaryoblastic Leukemia in a Lung Cancer Patient
por: Moon, Jung Joo, et al.
Publicado: (2014)

Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis
por: Bernau, Ksenija, et al.
Publicado: (2015)

Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization
por: Reed, Fiona E., et al.
Publicado: (2022)

Pediatric Non-Down Syndrome Acute Megakaryoblastic Leukemia With Unusual Immunophenotype
por: Koulmane Laxminarayana, Sindhura Lakshmi, et al.
Publicado: (2023)

Acute Megakaryoblastic Leukemia Developing as Donor Cell Leukemia after Umbilical Cord Blood Transplantation
por: Adachi, Yoshitaka, et al.
Publicado: (2017)

Acute mono-megakaryoblastic leukemia associated with extreme thrombocytosis and complex karyotype abnormalities
por: Hu, Rong, et al.
Publicado: (2013)

ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia
por: Sun, Xueqin, et al.
Publicado: (2017)

Acute megakaryoblastic blast crisis as a presentation manifestation of chronic myelogenous leukemia
por: Bhattacharya, Jenna B, et al.
Publicado: (2017)

BMP2K dysregulation promotes abnormal megakaryopoiesis in acute megakaryoblastic leukemia
por: Wang, Manman, et al.
Publicado: (2020)

Molecular Mechanisms of the Genetic Predisposition to Acute Megakaryoblastic Leukemia in Infants With Down Syndrome
por: Grimm, Juliane, et al.
Publicado: (2021)

Acute megakaryoblastic leukemia arising in a mediastinal mixed germ cell tumor
por: Alrohaibani, Alaaeddin, et al.
Publicado: (2021)

Megakaryoblasts in a newborn with Down syndrome
por: Buoro, Sabrina, et al.
Publicado: (2018)

LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia
por: Emmrich, Stephan, et al.
Publicado: (2014)

Improved outcome of pediatric patients with acute megakaryoblastic leukemia in the AML-BFM 04 trial
por: Schweitzer, Jana, et al.
Publicado: (2015)

Baicalein antagonizes acute megakaryoblastic leukemia in vitro and in vivo by inducing cell cycle arrest
por: Yu, Chunjie, et al.
Publicado: (2016)

Revealing the intratumoral heterogeneity of non-DS acute megakaryoblastic leukemia in single-cell resolution
por: Su, Narun, et al.
Publicado: (2022)

Surgical Pathology Resident Rotation Restructuring at a Tertiary Care Academic Center
por: Mehr, Chelsea R., et al.
Publicado: (2017)

Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models
por: Thiollier, Clarisse, et al.
Publicado: (2012)

Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1
por: Krawczyk, Krzysztof M., et al.
Publicado: (2017)

Alpha-Synuclein Expression in Acute Erythroleukaemia, Acute Megakaryoblastic Leukemia, and Normal Counterparts in Bone Marrow
por: Kosari, Farid, et al.
Publicado: (2017)

A case of KMT2A–SEPT9 fusion–associated acute megakaryoblastic leukemia
por: Forlenza, Christopher J., et al.
Publicado: (2018)

An intronic deletion in megakaryoblastic leukemia 1 is associated with hyperproliferation of B cells in triplets with Hodgkin lymphoma
por: Record, Julien, et al.
Publicado: (2020)

Case Report: The Value of Genomic Analysis in a Case of Megakaryoblastic Leukemia With Atypical Initial Manifestation
por: Gutiérrez-Jimeno, Miriam, et al.
Publicado: (2022)

Facilitating Test Status Information Communication in the Time of COVID-19
por: Master, Stephen R., et al.
Publicado: (2021)

Clinical utility of custom-designed NGS panel testing in pediatric tumors
por: Surrey, Lea F., et al.
Publicado: (2019)

Novel ATXN1/ATXN1L::NUTM2A fusions identified in aggressive infant sarcomas with gene expression and methylation patterns similar to CIC-rearranged sarcoma
por: Xu, Feng, et al.
Publicado: (2022)

Megakaryoblastic leukemia presenting as pancytopenia and extensive myelofibrosis in a child diagnosed by myeloid markers and CD 31
por: Majhi, Urmila, et al.
Publicado: (2012)

A Case of Pentasomy 21 With Two Isochromosome 21s in Acute Megakaryoblastic Leukemia Associated With Down Syndrome
por: Park, Yeongchun, et al.
Publicado: (2015)

Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS)
por: Pelleri, Maria Chiara, et al.
Publicado: (2014)

Establishment of Megakaryoblastic Cell Lines by Coinfection of Abelson Murine Leukemia Virus and Recombinant SV40‐retrovirus
por: Kajigaya, Sachiko, et al.
Publicado: (1988)

Tumor Necrosis Factor‐a Stimulates Colony Formation by a Megakaryoblastic Leukemia Cell Line, CMK
por: Akiyama, Yasuto, et al.
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_rbbqargpicvckt0s7pmfms5ep1