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Improving integrative 3D modeling into low‐ to medium‐resolution electron microscopy structures with evolutionary couplings

Electron microscopy (EM) continues to provide near‐atomic resolution structures for well‐behaved proteins and protein complexes. Unfortunately, structures of some complexes are limited to low‐ to medium‐resolution due to biochemical or conformational heterogeneity. Thus, the application of unbiased...

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Detalles Bibliográficos
Autores principales: McCafferty, Caitlyn L., Taylor, David W., Marcotte, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040867/
https://www.ncbi.nlm.nih.gov/pubmed/33759266
http://dx.doi.org/10.1002/pro.4067