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In Silico Analysis of High-Risk Missense Variants in Human ACE2 Gene and Susceptibility to SARS-CoV-2 Infection

SARS-CoV-2 coronavirus uses for entry to human host cells a SARS-CoV receptor of the angiotensin-converting enzyme (ACE2) that catalyzes the conversion of angiotensin II into angiotensin (1-7). To understand the effect of ACE2 missense variants on protein structure, stability, and function, various...

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Detalles Bibliográficos
Autores principales:	Saih, Asmae, Baba, Hana, Bouqdayr, Meryem, Ghazal, Hassan, Hamdi, Salsabil, Kettani, Anass, Wakrim, Lahcen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040925/ https://www.ncbi.nlm.nih.gov/pubmed/33884270 http://dx.doi.org/10.1155/2021/6685840

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