Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes

Over the past decade, immunotherapies have revolutionized the treatment of cancer. Although the success of immunotherapy is remarkable, it is still limited to a subset of patients. More than 1500 clinical trials are currently ongoing with a goal of improving the efficacy of immunotherapy through co-...

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Detalles Bibliográficos
Autores principales: Marín-Jiménez, Juan A., Capasso, Anna, Lewis, Matthew S., Bagby, Stacey M., Hartman, Sarah J., Shulman, Jeremy, Navarro, Natalie M., Yu, Hui, Rivard, Chris J., Wang, Xiaoguang, Barkow, Jessica C., Geng, Degui, Kar, Adwitiya, Yingst, Ashley, Tufa, Dejene M., Dolan, James T., Blatchford, Patrick J., Freed, Brian M., Torres, Raul M., Davila, Eduardo, Slansky, Jill E., Pelanda, Roberta, Eckhardt, S. Gail, Messersmith, Wells A., Diamond, Jennifer R., Lieu, Christopher H., Verneris, Michael R., Wang, Jing H., Kiseljak-Vassiliades, Katja, Pitts, Todd M., Lang, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8040953/
https://www.ncbi.nlm.nih.gov/pubmed/33854497
http://dx.doi.org/10.3389/fimmu.2021.607282

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