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Severe oligomeric tau toxicity can be reversed without long-term sequelae
Tau is a microtubule stabilizing protein that forms abnormal aggregates in many neurodegenerative disorders, including Alzheimer’s disease. We have previously shown that co-expression of fragmented and full-length tau in P301SxTAU62(on) tau transgenic mice results in the formation of oligomeric tau...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041046/ https://www.ncbi.nlm.nih.gov/pubmed/33484116 http://dx.doi.org/10.1093/brain/awaa445 |