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A Fast Multi-Locus Ridge Regression Algorithm for High-Dimensional Genome-Wide Association Studies

The mixed linear model (MLM) has been widely used in genome-wide association study (GWAS) to dissect quantitative traits in human, animal, and plant genetics. Most methodologies consider all single nucleotide polymorphism (SNP) effects as random effects under the MLM framework, which fail to detect...

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Detalles Bibliográficos
Autores principales:	Zhang, Jin, Chen, Min, Wen, Yangjun, Zhang, Yin, Lu, Yunan, Wang, Shengmeng, Chen, Juncong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041068/ https://www.ncbi.nlm.nih.gov/pubmed/33854527 http://dx.doi.org/10.3389/fgene.2021.649196

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