Cargando…
In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model
There is no FDA approved therapy for the treatment of celiac disease (CeD), aside from avoidance of dietary gluten. Larazotide acetate (LA) is a first in class oral peptide developed as a tight junction regulator, which is a lead candidate for management of CeD. A delayed release formulation was tes...
Autores principales: | Enomoto, Hiroko, Yeatts, James, Carbajal, Liliana, Krishnan, B. Radha, Madan, Jay P., Laumas, Sandeep, Blikslager, Anthony T., Messenger, Kristen M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041193/ https://www.ncbi.nlm.nih.gov/pubmed/33844694 http://dx.doi.org/10.1371/journal.pone.0249179 |
Ejemplares similares
-
Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions
por: Slifer, Zachary M., et al.
Publicado: (2021) -
A Randomized, Double-Blind Study of Larazotide Acetate to Prevent the Activation of Celiac Disease During Gluten Challenge
por: Leffler, Daniel A, et al.
Publicado: (2012) -
In silico Analysis Revealed Potential Anti-SARS-CoV-2 Main Protease Activity by the Zonulin Inhibitor Larazotide Acetate
por: Di Micco, Simone, et al.
Publicado: (2021) -
Zonulin Antagonist, Larazotide (AT1001), As an Adjuvant Treatment for Multisystem Inflammatory Syndrome in Children: A Case Series
por: Yonker, Lael M., et al.
Publicado: (2022) -
Peptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation
por: Di Micco, Simone, et al.
Publicado: (2021)