Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection

Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and immunity and can be therapeutically targeted. The role of epigenetic regulator...

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Detalles Bibliográficos
Autores principales: Parmar, Naveen, Burrows, Kyle, Vornewald, Pia M., Lindholm, Håvard T., Zwiggelaar, Rosalie T., Díez-Sánchez, Alberto, Martín-Alonso, Mara, Fosslie, Madeleine, Vallance, Bruce A., Dahl, John Arne, Zaph, Colby, Oudhoff, Menno J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041206/
https://www.ncbi.nlm.nih.gov/pubmed/33788902
http://dx.doi.org/10.1371/journal.ppat.1009476

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